Magazine de la santé : AlloDocteur

Imagerie : repousser les frontières de l’invisible Les premiers microscopes ont permis de mettre au jour l’existence des bactéries et de tout juste deviner leur forme. Les technologies récompensées par le dernier prix Nobel de chimie permettent de décrypter des structures beaucoup plus petites. À Lille, cette imagerie qui utilise des lasers très particuliers est En savoir plus surMagazine de la santé : AlloDocteur[…]

Structured illumination microscopy and correlative microscopy to study autophagy

Autophagy Volume 75, 15 March 2015, Pages 61–68

Autophagy is a predominant eukaryotic mechanism for the engulfment of “portions” of cytoplasm allowing their degradation to recycle metabolites. The autophagy is ubiquitous among the life kingdom revealing the importance of this pathway that appears more complex than previously thought. Several reviews have already addressed how to monitor this pathway and have highlighted the existence of new routes such as the LC3-associated phagocytosis (LAP) and the non-canonical autophagy. The principal difference between autophagosomes and LAP vacuoles is that the former has two limiting membranes positives for LC3 whereas the latter has one.  […]