ESCRT‐mediated lysosome repair precedes lysophagy and promotes cell survival

DOI 10.15252/embj.201899753 | Published online 12.10.2018 The EMBO Journal (2018) e99753 Although lysosomes perform a number of essential cellular functions, damaged lysosomes represent a potential hazard to the cell. Such lysosomes are therefore engulfed by autophagic membranes in the process known as lysophagy, which is initiated by recognition of luminal glycoprotein domains by cytosolic lectins En savoir plus surESCRT‐mediated lysosome repair precedes lysophagy and promotes cell survival[…]