Sébastien Janel

Ingénieur de Recherche CN CNRS Google Scholar – ORCiD Atomic force microscopy applied to microbiology: topography, adhesion & mechanical properties of biological samples. In charge of the AFM facility in Institut Pasteur de Lille (6 instruments). Teaching students, promoting the AFM for bio labs and the general public. → Atomic Force Microscopy in the lab En savoir plus surSébastien Janel[…]

Fifteen years of Servitude et Grandeur to the application of a biophysical technique in medicine: The tale of AFMBioMed

 18 December 2018 – https://doi.org/10.1002/jmr.2773 AFMBioMed is the founding name under which international conferences and summer schools are organized around the application of atomic force microscopy in life sciences and nanomedicine. From its inception at the Atomic Energy Commission in Marcoule near 2004 to its creation in 2007 and to its 10th anniversary conference in Krakow, En savoir plus surFifteen years of Servitude et Grandeur to the application of a biophysical technique in medicine: The tale of AFMBioMed[…]

Rejoigniez-nous

Post-Doc Aucun poste disponible pour le moment. Thèses Two positions available for Early Stage Researchers (ESRs) at Institut Pasteur de Lille (France). The two positions opened at the Cellular Microbiology and Physics of Infection Group – Center for Infection and Immunity of Lille, are aimed at the experimental investigation of the mechanical properties of cells En savoir plus surRejoigniez-nous[…]

Lab members

MEMBRES ACTIFS Frank Lafont (DR1 CNRS IPL) Catherine Daniel (CR IPL) Vincent Dupres (MCU Univ Lille – Med Fac) – Javier López (PhD ITN) Ghaffar Muharram (MCU Univ Lille – Sci Fac) Lorena Redondo-Morata (CR2 Inserm) – Maria Luisa Marini (PhD ITN) – Fabio Perissinotto (Post-Doc INSERM) Sébastien Janel (IR2 CNRS) Sabine Poiret (Tec IPL) Elisabeth Werkmeister (IR2 CNRS) Marie-Christine Renaud (Gestionnaire IPL) L’équipe du CMPI soutient la Recherche En savoir plus surLab members[…]

Clag9 is not essential for PfEMP1 surface expression in non-cytoadherent Plasmodium falciparum parasites with a chromosome 9 deletion

PLoS One. 2011;6(12):e29039. doi: 10.1371/journal.pone.0029039.

BACKGROUND
The expression of the clonally variant virulence factor PfEMP1 mediates the sequestration of Plasmodium falciparum infected erythrocytes in the host vasculature and contributes to chronic infection. Non-cytoadherent parasites with a chromosome 9 deletion lack clag9, a gene linked to cytoadhesion in previous studies. Here we present new clag9 data that challenge this view and show that surface the non-cytoadherence phenotype is linked to the expression of a non-functional PfEMP1. […]