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Our research is divided into two main areas, including technological developments and the use of different experimental systems to address several aspects involved in the early stages of infection
We develop an inter-disciplinary approach
Our working hypothesis suggests that the viscoelastic properties of biological membranes participate in the regulation of the implementation of cell signaling complexes in response to a stimulus. The stimulus we choose is the host-pathogenic interaction that has the advantage of exacerbating the cell response. The signaling pathway is the activation of autophagy in response to infection. The methodology we are deploying is based on a correlative approach between force spectroscopy and super-resolution photonic and electron microscopy.
Lab members

Catherine Daniel
Chargée de Recherche – IPL

Vincent DUPRES
Maître de Conférence – Université de Lille

Ghaffar MUHARRAM
Associate professor/chair of excellence – University Lille 2/INSERM

Nicolas BAROIS
Ingénieur de Recherche – INSERM
Responsable de la microscopie électronique

Elisabeth Werkmeister
Ingénieure de Recherche – CNRS
Microscopie photonique de super-résolution et analyse d’images.

Fabio Perissinotto
Post-Doc – INSERM
Assembly and release of SNAREpins in the membrane for synaptic transmission

Sabine Poiret
Technicienne – Institut Pasteur de Lille

Maria Luisa Marini
PhD Marie Skłodowska-Curie Innovative Training Networks

Javier López Alonso
PhD Marie Skłodowska-Curie Innovative Training Networks

Ahmad Melhem
Stagiaire

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