Cellular Microbiology and Physics of Infection

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Persistence and dynamics of fluorescent Lactobacillus plantarum in the healthy versus inflamed gut
Assessment of Pb(II), Cd(II), and Al(III) Removal Capacity of Bacteria from Food and Gut Ecological Niches: Insights into Biodiversity to Limit Intestinal Biodisponibility of Toxic Metals
Correlative Microscopy Using Scanning Probe Microscopes
2,6-Diaminopurine as a highly potent corrector of UGA nonsense mutations
Rab11A regulates dense granule transport and secretion during Toxoplasma gondii invasion of host cells and parasite replication
Galectin-3 modulates epithelial cell adaptation to stress at the ER-mitochondria interface
High‐dose dietary supplementation with zinc prevents gut inflammation: Investigation of the role of metallothioneins and beyond by transcriptomic and metagenomic studies
Wattignies: Ils sont collégiens et apprentis chercheurs à Pasteur
Norovirus, qu’est-ce-que c’est? France Bleu
The laboratory celebrates the 80th anniversary of the CNRS
Blocking bacterial entry at the adhesion step reveals dynamic recruitment of membrane and cytosolic probes
Stiffness tomography of eukaryotic intracellular compartments by atomic force microscopy
Our research is divided into two main areas, including technological developments and the use of different experimental systems to address several aspects involved in the early stages of infection
We develop an inter-disciplinary approach

Our working hypothesis suggests that the viscoelastic properties of biological membranes participate in the regulation of the implementation of cell signaling complexes in response to a stimulus. The stimulus we choose is the host-pathogenic interaction that has the advantage of exacerbating the cell response. The signaling pathway is the activation of autophagy in response to infection. The methodology we are deploying is based on a correlative approach between force spectroscopy and super-resolution photonic and electron microscopy.

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Lab members

Frank LAFONT

Directeur de Recherche – CNRS
Directeur du laboratoire – Curriculum

Vincent DUPRES

Maître de Conférence – Université de Lille

Nicolas BAROIS

Ingénieur de Recherche – INSERM
Responsable de la microscopie électronique

Sébastien JANEL

Ingénieur de Recherche – CNRS
Microscopie à force atomique – Curriculum

Elisabeth Werkmeister

Ingénieure de Recherche – CNRS
Microscopie photonique de super-résolution et analyse d’images.

Fabio Perissinotto

Post-Doc – INSERM
Assembly and release of SNAREpins in the membrane for synaptic transmission

Sabine Poiret

Technicienne – Institut Pasteur de Lille

Javier López Alonso

PhD Marie Skłodowska-Curie Innovative Training Networks

Ahmad Melhem

Stagiaire

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Our networks

GDR: Microscopie et imagerie du vivant - Approches quantitatives du vivant - Cosm’actif

Eu cost: afm4nanomed&bio - transautophagy - moebieu

Eu itn (H2020 marie-curie prgm): phys2biomeb

Réseaux technologiques: remisol - rtmfm - rccm

Société savantes: sbcf - cfatg - SFB-GEM

Elmi

FSL